The Call of Cthulhu roleplaying game is set in the world of H. P. Lovecraft and places the characters in direct confrontation with the forces of the Cthulhu Mythos. Most commonly the setting is in the 1920′s although earlier and later settings are covered by the rules. The game is somewhat unique in that the ‘heros’ are not particularly special. They are usually everyday people who happen to be caught up in things. The games are also often very focused on an investigation of some occurence, or some great evil. Investigators (as the heros are called in the game) are often called upon to uncover the evil machinations of dark cults, or the malevolent workings of deranged madmen.
The setting for VtM is one of a dark gothic near future where Vampires live in communities, often fighting over resources and power. Humans are treated with a mixture of contempt, need for control, as food and often with envy. A powerful theme throughout the game is the loss of humanity. The more you act like a Vampire, the less human you will be, and thus, the less control you will have over yourself. In the end the setting is very rich, with the sourcebooks being well written enough to be read cover to cover.